Overview

Vision Restoration With a Collagen Crosslinked Boston Keratoprosthesis Unit

Status:
Completed
Trial end date:
2021-08-31
Target enrollment:
Participant gender:
Summary
This is a phase I/II prospective, randomized, multi-center, double-masked, vehicle-controlled clinical trial evaluating the safety and efficacy of corneal collagen cross-linking the keratoprosthesis carrier tissue in subjects who are candidates for high-risk keratoprosthesis implantation but because of a history of corneal melts or autoimmune diseases are not candidate for a traditional corneal transplant.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Joseph B. Ciolino, MD
Collaborator:
United States Department of Defense
Treatments:
Dextrans
Riboflavin
Vitamins