Overview

Viokase 16, Viokase16 Plus Nexium and Nexium Alone

Status:
Terminated
Trial end date:
2012-03-01
Target enrollment:
Participant gender:
Summary
Our primary hypothesis is that the addition of Nexium to Viokase 16 will decrease the chronic abdominal pain in patients with small duct chronic pancreatitis in a superior fashion compared to Viokase 16 plus placebo or to Nexium alone. A secondary hypothesis would be an increase in quality of life. Our objective is to elucidate the role of Nexium in the control of pancreatic pain, quality of life, and narcotic usage alone or when added to Viokase 16. Our endpoints are the reduction of abdominal pain, decreased pain medication usage, decreased ER visits and decreased hospital admissions for abdominal pain.
Phase:
Phase 1
Details
Lead Sponsor:
University of Florida
Collaborator:
AstraZeneca
Treatments:
Esomeprazole
Pancreatin
Pancrelipase