Vinorelbine for Children With Progressive or Recurrent Low-grade Gliomas
Status:
Completed
Trial end date:
2017-07-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to investigate whether weekly Vinorelbine treatment can shrink
or slow the growth of pediatric low-grade gliomas that have either returned or are continuing
to grow.
Vinorelbine is a semi-synthetic vinca alkaloid that has recently generated interest in
patients with pediatric low-grade glioma. It has been specifically synthesized to broaden its
therapeutic spectrum and decrease the neurotoxicity associated with related agents.