Vinorelbine and Celecoxib in Treating Women With Relapsed or Metastatic Breast Cancer
Status:
Terminated
Trial end date:
2005-02-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Celecoxib may stop the growth of tumor cells by blocking the enzymes necessary for
tumor cell growth. Drugs used in chemotherapy, such as vinorelbine, work in different ways to
stop tumor cells from dividing so they stop growing or die. Combining vinorelbine with
celecoxib may kill more tumor cells.
PURPOSE: Phase I trial to determine the effectiveness of combining vinorelbine with celecoxib
in treating women who have relapsed or metastatic breast cancer.