Overview

Vinorelbine/Gemcitabine Versus Vinorelbine/Carboplatin in Advanced Non-small Cell Lung Cancer

Status:
Completed
Trial end date:
2011-02-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to explore if the combination of vinorelbine and gemcitabine is better than vinorelbine and carboplatin in the treatment of advanced non-small cell lung cancer, in terms of survival, quality of life and need for palliative radiotherapy.
Phase:
Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
The Norwegian Lung Cancer Study Group
Treatments:
Carboplatin
Gemcitabine
Vinblastine
Vinorelbine
Criteria
Inclusion Criteria:

- Non-small cell lung cancer stage IIIB or IV

- Not eligible for radical radiotherapy or surgery

- WHO performance status 0-2

Exclusion Criteria:

- Pregnancy

- Other clinical active cancer disease

- ALAT/ALP more than 3 times upper normal limit, bilirubin >1.5 upper limit

- Bowel disease that causes malabsorption