Vinflunine and Erlotinib or Pemetrexed in Treating Patients With Unresectable or Metastatic Solid Tumors
Status:
Completed
Trial end date:
2010-01-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as vinflunine, work in different ways to stop the
growth of tumor cells, either by killing the cells or by stopping them from dividing.
Erlotinib and pemetrexed may stop the growth of tumor cells by blocking some of the enzymes
needed for cell growth. Giving vinflunine together with erlotinib or pemetrexed may kill more
tumor cells.
PURPOSE: This phase I trial is studying the side effects and best dose of vinflunine when
given together with erlotinib or pemetrexed in treating patients with unresectable or
metastatic solid tumors.