Vildagliptin and the Glucagon Response to Hypoglycemia in Type 1 Diabetes

• Status: Completed
• Trial end date: 2011-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The study examines whether DPP-4 inhibition by vildagliptin affects the glucagon counterregulatory response to hypoglycemia in type 1 diabetes.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Lund University
• Treatments: Glucagon; Glucagon-Like Peptide 1; Vildagliptin

Criteria

Inclusion Criteria:

• Type 1 diabetes

• Age >18 years

• HbA1c 6.5-8,5%

Exclusion Criteria:

• Pregnancy

• Lactation

• Acute infection

• Liver disease

• Treatment with cortisol