Vigabatrin Ph 1 Cocaine Interaction Study

• Status: Completed
• Trial end date: 2010-10-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a Phase 1 safety/tolerably study to determine if there are clinically significant interactions between oral vigabatrin (gamma vinyl-gamma-amino butyric acid; VGB) concurrent with intravenous (IV) cocaine infusions.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Institute on Drug Abuse (NIDA)
• Treatments: Central Nervous System Stimulants; Cocaine; gamma-Aminobutyric Acid; Vigabatrin

Criteria

Inclusion Criteria:

• Be between 18 and 45 years of age, inclusive

• Currently be a non-treatment seeking cocaine user as confirmed by a positive urine test for cocaine

• Able to provide written informed consent

• A negative pregnancy test within 72 hours prior to receiving the first infusion of cocaine

Exclusion Criteria:

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