Video-assisted Thoracoscopic Surgery - Exparel Study

• Status: Recruiting
• Trial end date: 2023-07-31
• Target enrollment: 0
• Participant gender: All

Summary

Video-assisted thoracoscopic surgery (VATS) greatly decreased the number and types of surgery that required open thoracotomy. Initially it was thought that VATS would lead to a reduction of respiratory problems and less acute pain in patients when compared to patients receiving an open thoracic surgery. However, for reasons not clearly understood, a large number of patients who undergo VATS still experience moderate to severe post-surgical pain (1). Physicians are still faced with the challenge of providing care that will manage both the respiratory issues as well as manage acute pain. The goal of this study is to find the most suitable regimen to effectively manage post-VATS-related pain.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Rakesh Sondekoppam Vijayashankar; YATISH SIDDAPURA RANGANATH
• Collaborator: American Society of Regional Anesthesia
• Treatments: Bupivacaine

Criteria

Inclusion Criteria:

• Age over 18 years and less than 80 years

• Undergoing video-assisted thoracoscopic surgery (VATS) procedure

• BMI less than 40

Exclusion Criteria:

• Unable to provide informed consent

• Non-English speaking

• Pregnant

• BMI greater than 40

• Video-assisted thoracoscopic surgery pleurodesis subjects

• Patients with pre-existing chronic pain

• Opioid tolerance

• Pain syndromes including fibromyalgia, regional pain syndrome or post therapeutic neuralgia in a thoracic distribution

• Allergy to the study medication

• Patients with infectious disease

• Patients with impaired coagulation

• Severe hepatic disease

• Incarcerated