Very Intense Radiotherapy-Chemotherapy Regimen in Advanced HNSCC
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Altered fractionated radiotherapy and concomitant radio-chemotherapy have been shown to be
two possibilities for improving efficacy of radiotherapy in locally advanced head and neck
carcinomas. In this multicentric study, we tested the hypothesis that accelerated
radiotherapy could be delivered concomitantly with conventional high doses of CDDP-5FU,
aiming to improve both local control and on distant metastases as compared to very
accelerated radiotherapy.