Verify if Amelogenins Had Some Benefits in Improving Lower 2nd Molar Periodontal Healing After 3rd Molar Extraction
Status:
Completed
Trial end date:
2018-04-20
Target enrollment:
Participant gender:
Summary
Background: Prevention of periodontal defects after the extraction of lower third molars
remains a challenge. Various methods have been proposed in the literature, but there are no
studies which evaluated the effectiveness of amelogenins.
Methods: A single-blind split-mouth randomized controlled clinical trial (RCT) was performed
on 5 patients to verify if amelogenins had some benefits in improving lower second molar
periodontal healing after adjacent third molar extraction. A PPD ≥ 8 mm associated with a
radiographic bone defect of at least 5 mm were the main inclusion criteria.