Vericiguat Drug-drug Interaction With Nitroglycerin in Stable Coronary Artery Disease Patients
Status:
Completed
Trial end date:
2016-08-01
Target enrollment:
Participant gender:
Summary
This study is intended to investigate the effect of nitroglycerin on vericiguat in patients
with stable coronary artery disease (CAD). Nitroglycerin is the standard therapy to treat
acute crisis of angina. Thus there is a high likelihood of co-administration of both drugs in
the target indication of vericiguat, worsening heart failure (HF). Therefore, it is important
to investigate the safety and tolerability of vericiguat and nitroglycerin, which may be used
as unprescribed on-demand treatment by patients with acute episodes of angina pectoris.