Verapamil vs. Sertraline for Vestibular Migraine & Chronic Subjective Dizziness
Status:
Completed
Trial end date:
2014-10-01
Target enrollment:
Participant gender:
Summary
Vestibular migraine (VM) and chronic subjective dizziness (CSD) commonly cause vertigo,
unsteadiness and dizziness. Clinical investigators are studying these illnesses to understand
them better. VM and CSD occur together in about 1/3 of patients. That makes it hard to
diagnose them accurately and decide what treatments to use. As a result, doctors and patients
may be confused about these diagnoses. The goal of this study was use two different
medications to tease apart the symptoms of VM and CSD.
Patients who have VM and CSD together were given either verapamil or sertraline for 12 weeks.
These medications are used to treat VM and CSD, though they are not approved for this
purpose. Verapamil is believed to have stronger effects on symptoms of VM. Sertraline is
believed to have stronger effects on symptoms of CSD. By comparing the responses of patients
to these two medications, the researchers hoped to learn more about the key features of VM
and CSD.