Overview

Venetoclax-Dexamethasone in Relapsed and/or Refractory t(11;14) Amyloidosis

Status:
Not yet recruiting
Trial end date:
2026-09-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is assess safety, safest dose, and effectiveness of venetoclax in combination with dexamethasone in participants with t(11;14) positive relapsed (comes back) or refractory (did not get better) light chain amyloidosis.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Rajshekhar Chakraborty, MD
Collaborator:
Genentech, Inc.
Treatments:
BB 1101
Bendamustine Hydrochloride
Daratumumab
Dexamethasone
Dexamethasone acetate
Ixazomib
Pomalidomide
Venetoclax