Venetoclax Combined With ATRA and ATO in Hyperleukocytic Acute Promyelocytic Leukemia
Status:
ACTIVE_NOT_RECRUITING
Trial end date:
2027-07-01
Target enrollment:
Participant gender:
Summary
This study aims to evaluate the safety and effectiveness of combining venetoclax with all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) in patients with newly diagnosed acute promyelocytic leukemia (APL) who have very high white blood cell counts. APL is a rare type of blood cancer, and patients with high white blood cell levels often face serious complications. Current treatments with ATRA and ATO are effective, but the outcomes for patients with high white blood cells remain poor. This study will test whether adding venetoclax, a drug that helps leukemia cells die, can improve treatment results.
Phase:
NA
Details
Lead Sponsor:
Anhui Medical University
Collaborator:
The First Affiliated Hospital of Anhui Medical University