Overview

Venetoclax + Azacitidine vs. Induction Chemotherapy in AML

Status:
Recruiting
Trial end date:
2023-06-30
Target enrollment:
Participant gender:
Summary
This research is being done to assess the therapeutic activity of a promising combination (azacitidine and venetoclax) versus conventional cytotoxic chemotherapy in induction-eligible patients with acute myeloid leukemia. This study involves the following: - Venetoclax and azacitidine (investigational combination) - Cytarabine and idarubicin or daunorubicin (per standard of care) or Liposomal daunorubicin and cytarabine (per standard of care)
Phase:
Phase 2
Details
Lead Sponsor:
Massachusetts General Hospital
Collaborator:
AbbVie
Treatments:
Azacitidine
Cytarabine
Daunorubicin
Idarubicin
Venetoclax