Overview

Velcade Plus ICE for Patients With Relapsed Classical Hodgkin Lymphoma

Status:
Completed
Trial end date:
2012-06-01
Target enrollment:
Participant gender:
Summary
Primary Objectives: 1. To determine the toxicity profile of multiple doses of bortezomib when given with ICE in patients with relapsed and refractory classical Hodgkin lymphoma (HL). 2. To determine the maximum tolerated dose (MTD) of bortezomib when given in combination with ICE chemotherapy in patients with relapsed and refractory classical Hodgkin lymphoma (HL). Secondary Objectives: - To determine the overall response rate and complete response rate in patients with relapsed and refractory classical Hodgkin lymphoma (HL).
Phase:
Phase 1
Details
Lead Sponsor:
M.D. Anderson Cancer Center
Collaborator:
Millennium Pharmaceuticals, Inc.
Treatments:
Bortezomib
Carboplatin
Etoposide
Etoposide phosphate
Ifosfamide
Isophosphamide mustard
Mesna