Overview

Vasoreactivity in Carriers of Genetic Polymorphisms

Status:
Unknown status
Trial end date:
2006-12-01
Target enrollment:
Participant gender:
Summary
The objective of the study is to assess the impact of genetic variation (especially polymorphisms of the gene coding endothelial nitric oxide synthase (eNOS) and the bradykinin B2 receptor gene) on venous and arterial responsiveness to vasodilators in healthy individuals without cardiovascular risk factors.
Phase:
Phase 1
Details
Lead Sponsor:
Heidelberg University
Treatments:
Acetylcholine
Bradykinin
Kininogens
Nitroprusside