Vasopressin and Epinephrine Versus Epinephrine Alone in Cardiac Arrest
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Recent studies have suggested that arginine-vasopressin could be more effective in the
treatment of cardiac arrests. The last published study did not outline obvious improvements
in the prognosis of all cardiac arrests but pointed out a possible increased survival rate
when arginine-vasopressin is associated with epinephrine. The aim of this study is to compare
the efficacy of two successive injections of epinephrine (1 mg) with two successive
injections of epinephrine associated with arginine-vasopressin (40 UI) in out-of-hospital
cardiac arrests occurring in adult patients. The primary endpoint is the survival rate at
hospital admission. The inclusion period lasts 18 months and 2416 patients are planned to be
enrolled.