Vasopressin Administration During Laparoscopic Myomectomy: a Randomized Controlled Trial
Status:
Completed
Trial end date:
2015-06-01
Target enrollment:
Participant gender:
Summary
The main purpose of this study is to compare blood loss at the time of laparoscopic or
robotically-assisted laparoscopic myomectomy when using different amounts of dilute
vasopressin solution. Myomectomy is a surgical procedure to remove fibroids from the uterus.
Vasopressin is a synthetic drug used to help decrease blood loss at the time of gynecologic
surgery; although very little is know about the optimal dosage and administration.
The investigators plan to perform a randomized clinical trial on patients scheduled for
minimally invasive myomectomy. All patients will get the same overall amount of vasopressin.
Patients will be assigned by chance to one of two groups: one group will receive higher
volume of a more dilute vasopressin solution. The other group will receive a lower volume of
a more concentrated solution. The investigators will collect information on operative blood
loss and complications related to surgery.
Phase:
Phase 4
Details
Lead Sponsor:
Brigham and Women's Hospital
Collaborators:
Beth Israel Deaconess Medical Center Cedars-Sinai Medical Center North Shore Medical Center