Vascular Function, Endothelin, and Inflammation in Pre-diabetic Obesity Versus Lean Healthy Controls
Status:
Terminated
Trial end date:
2010-08-01
Target enrollment:
Participant gender:
Summary
Aims:
1. Does inflammation contribute importantly to concurrent defects in vascular and metabolic
dysfunction in human pre-diabetic obesity?
2. Are there benefits of anti-inflammatory treatment strategies in pre-diabetic obesity in
the context of existing treatment with metformin?
3. Are there benefits of anti-inflammatory treatment strategies in pre-diabetic obesity in
the context of existing treatment with lisinopril?