Overview

Vascular Endothelial Protection Effects of Dextromethorphan

Status:
Completed
Trial end date:
2005-12-01
Target enrollment:
0
Participant gender:
Male
Summary
To test the hypothesis that DM could have anti-inflammatory effect and thus achieve vascular protection effect on heavy smokers.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
National Cheng-Kung University Hospital
Treatments:
Dextromethorphan
Criteria
Inclusion Criteria:

- healthy male volunteers who are currently smoking

Exclusion Criteria:

- personal history of hypertension or diabetes mellitus

- family history with

- documented premature cardiovascular events

- cardiovascular-associated sudden death

- total cholesterol > 240 mg/dL

- triglyceride > 200 mg/dL

- low-density lipoprotein > 160 mg/dL.