Varenicline-Methamphetamine Interaction Study (2008)
Status:
Withdrawn
Trial end date:
2008-08-01
Target enrollment:
Participant gender:
Summary
The primary aim of the study is to determine the safety and tolerability of treatment with
Varenicline in methamphetamine-dependent volunteers. The investigators also seek to determine
the effects of treatment with Varenicline, as compared to placebo, on craving for
methamphetamine or cigarettes following exposure to methamphetamine and smoking cues,
respectively. The effects of treatment with Varenicline, as compared to placebo, on
subjective effects produced by administration of methamphetamine or placebo will be attempted
to be determined. Lastly, the investigators hope to determine the effects of treatment with
Varenicline, as compared to placebo, on reinforcing effects produced by administration of
methamphetamine or placebo.