Overview

Varenicline For Vaping Cessation In Non Smoker Vaper Adolescents

Status:
Not yet recruiting
Trial end date:
2025-12-01
Target enrollment:
Participant gender:
Summary
The Investigators propose a randomized, placebo-controlled trial to test the hypothesis that varenicline added to group behavioral and texting support will be well tolerated and improve vaping cessation rates over behavioral treatment alone in nicotine-dependent adolescents who vape, do not smoke, and want to quit. To do so, the investigators propose to enroll 300 adolescents in Greater Boston meeting these criteria in a double-blind, placebo-controlled, parallel group, study of varenicline up to 1 mg bid for 12 weeks added to 12 weeks of group behavioral and texting support specifically designed for teen vaping cessation.
Phase:
Phase 4
Details
Lead Sponsor:
Massachusetts General Hospital
Collaborator:
National Institute on Drug Abuse (NIDA)
Treatments:
Varenicline