Overview
Vancomycin in the Target Site Treatment of Intracranial Infection
Status:
Unknown status
Unknown status
Trial end date:
2018-12-01
2018-12-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
Vancomycin, a novel intravenously administered antibiotic, currently plays a key role in the management of complicated multi-organism infections. However,current LC-MS/MS methods briefly describe parameters and the only reported internal standard was sometimes difficult to obtain. In our study,an updated LC-MS/MS method for the quantitative analysis of vancomycin in human serum was developed.Phase:
Phase 4Accepts Healthy Volunteers?
NoDetails
Lead Sponsor:
Xijing HospitalTreatments:
Vancomycin
Criteria
Inclusion Criteria:In ICU; ventricle drainage was carried out; renal function is normal, namely creatinine
clearance rate is >60ml/min;
Exclusion Criteria:
women in pregnancy or lactation;in patients with renal insufficiency, the creatinine
clearance rate (Clcr) is less than 60ml/min.