Vancomycin Powder Combined With Autogenous Bone Graft as a Prevention for Post-operative Infection for Spine Surgery

• Status: Recruiting
• Trial end date: 2027-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Deep surgical site infection (DSSI) is one of the most challenging complications for spinal surgeons and can lead to a poor clinical outcome. This ambispective study was designed to examine the effect of vancomycin powder mixed with autogenous bone graft and bone substitute on preventing deep surgical site infection (DSSI) in degenerative lumbar fusion surgeries as well as any interference with bony fusion.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Taipei Veterans General Hospital, Taiwan
• Treatments: Vancomycin

Criteria

Inclusion Criteria:

• Patients who have instrumented spine fusion surgery due to failed conservative treatment (bed rest, medication, rehabilitation programs) for 3 to 6 months

• Patients who are willing to sign the surgical permit after the surgeon explains all surgical procedures along with the surgical risks

• Patients who fully understand the surgical procedures as well as the surgical risks and are willing to sign the surgical permit and the inform consent

• Patients who agree one more blood withdrawal after operation

Exclusion Criteria:

• Patients who agree to accept the spine surgery but do not agree to sign the inform consent

• Patients who have allergic reaction to vancomycin