Overview

Vancomycin Plus Moxifloxacin Versus Vancomycin Plus Ceftazidime for the Treatment of Peritoneal Dialysis (PD)-Related Peritonitis

Status:
Completed

Trial end date:
2016-04-01

Target enrollment:

Participant gender:

Summary

Intra-peritoneal administration of antibiotics covering both gram-positive and gram-negative organisms was recommended as first-line regimen for the management of peritoneal dialysis related peritonitis. Oral administration of quinolones can also achieve effective serum concentrations, and is more convenient and economical. We conducted a pilot randomized controlled study to compare the effects on peritonitis cure and relapsing rates between oral moxifloxacin plus IP vancomycin and conventional IP vancomycin plus ceftazidime.

Phase:

N/A

Details

Lead Sponsor:

Peking University First Hospital

Treatments:

Ceftazidime
Fluoroquinolones
Moxifloxacin
Norgestimate, ethinyl estradiol drug combination
Vancomycin