Value of Ondansetron Medication vs Inhaled Isopropyl Therapy in the Emergency Department (VOMIITED)

• Status: Recruiting
• Trial end date: 2021-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will compare two different ways to relieve nausea and vomiting in the Emergency Department. The usual treatment for nausea/vomiting is a drug called Zofran, but new studies have suggested that smelling alcohol pads can also help to relieve nausea and vomiting.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Texas Tech University Health Sciences Center, El Paso
• Treatments: Ethanol; Ondansetron

Criteria

Inclusion Criteria:

• Patients aged 18-65 years presenting to the emergency department complaining of current nausea with or without episodes of emesis beginning within the previous 24hrs

Exclusion Criteria:

• Patients with known allergy to isopropyl alcohol

• Patients outside of the defined age range

• Patients with an inability to inhale through the nares (including recent upper respiratory infection)

• Patients greater than 20 weeks estimated gestation

• Patients with past medical history of gastroparesis, or hemoptysis

• Patients who have taken an antiemetic medication in the past 48 hours

• Patients demonstrating hemodynamic instability with systolic blood pressure <90 or tachycardia >120 bpm