Overview

Valchlor in the Treatment of Lichen Planopilaris

Status:
Completed
Trial end date:
2019-08-30
Target enrollment:
Participant gender:
Summary
The primary objective of this study is to assess the potential effectiveness of once daily application of Valchlor in decreasing disease activity in patients with Lichen Planopilaris. The primary measurement of efficacy will be with the Lichen Planopilaris Activity Index (LPPAI) before and after 6 months of treatment. Secondary measures of efficacy will be the mean follicular density, Physician Global assessment (PGA) score, and the Dermatology Quality of Life Index (DQLI) score before and after six months of therapy.
Phase:
Phase 2
Details
Lead Sponsor:
Mayo Clinic
Collaborator:
Actelion
Treatments:
Mechlorethamine