Valacyclovir in Pain Management of Acute Apical Abscesses
Status:
Not yet recruiting
Trial end date:
2024-11-30
Target enrollment:
Participant gender:
Summary
The Virus in Endodontics (VE) phase I pilot study for preoperative pain will be analyzed and
adjusted for the Phase II clinical trial. The Phase II clinical trial on preoperative pain,
postoperative pain, and clinical healing will involve 250 patients. Patients will be
recruited from the same pool of participants as the Phase II clinical trial. Preoperative
cone beam computed tomography (CBCT) scans will be taken as well as three and six month
postoperative CBCT scans. The secondary outcomes form the Phase II randomized clinical trial
will be clinical success and visible radiographic healing determined by CBCT images.