Valacyclovir Suppression to Improve the Stability of Vaginal Flora Among HSV-2 Seropositive Women
Status:
Withdrawn
Trial end date:
2010-09-01
Target enrollment:
Participant gender:
Summary
We will be examining the effects of suppressive valacyclovir therapy on the stability of
vaginal flora in women who are seropositive for HSV-2. We have preliminary data that suggests
the presence of HSV-2 increases the risk for Group B Streptococcus colonization as well as
many other deleterious organisms (e.g. Streptococcus pseudoporcinus), in addition to
increasing the risk for acquisition of BV-associated vaginal flora. We will be examining the
effects of suppressive therapy on the vaginal flora of any HSV-2 seropositive woman.