Overview

Vaginal Estradiol Use in Pessary Care

Status:
Not yet recruiting
Trial end date:
2023-12-01
Target enrollment:
0
Participant gender:
Female
Summary
The primary outcome of this study compare the rate of pessary discontinuation at 6 months post-pessary fitting in women using vaginal estradiol versus those not using vaginal estradiol.
Phase:
Early Phase 1
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
University of South Florida
Treatments:
Estradiol
Criteria
Inclusion Criteria:

- Age ≥ 18 years

- Postmenopausal status

- Recent pessary fitting

- Office-based and home-based pessary care

Exclusion Criteria:

- Women < 18 years old

- Women currently on hormone replacement therapy (pill, patch, pellet)

- Women currently using vaginal estradiol cream within the last 4 weeks

- Medical contraindications to vaginal estradiol including unevaluated vaginal bleeding

- Inability to apply vaginal estradiol cream

- Inability to provide informed consent

- Inability to comprehend written and/or spoken English or Spanish

- Inability to comply with study visit schedule