Vaginal Diazepam for the Treatment of Female Pelvic Pain

• Status: Completed
• Trial end date: 2017-07-01
• Target enrollment: 0
• Participant gender: Female

Summary

To determine the efficacy of intravaginal diazepam for the treatment of pelvic pain associated with pelvic floor hypertonic disorder.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Missouri-Columbia
• Treatments: Diazepam

Criteria

Inclusion Criteria:

• Age 18 years old

• Primary complaint of acute or chronic pelvic pain with or without dyspareunia

• Physical exam findings consistent with levator muscle spasm

• Capable of inserting tablet in vagina without use of applicator.

Exclusion Criteria:

• Chronic narcotic use

• Non-English speaking

• Currently serving a prison sentence

• Stage III or greater vaginal prolapse

• Allergies or contraindications to benzodiazepines

• Pregnant or breastfeeding

• Currently receiving comprehensive pelvic floor rehabilitation therapy and/or vaginal valium therapy

• Unwilling or incapable of inserting tablet in vagina without applicator.