Vaginal Cleaning Using Povidone Iodine Before CS to Reduce Postoperative Wound Infection

• Status: Completed
• Trial end date: 2021-03-15
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of work to assess the effectiveness of preoperative vaginal cleansing with povidone iodine on reduction of post caesarean section wound infection

Research questions:

Does vaginal cleaning using povidone iodine before cesarean section has effect on reduction of postoperative wound infection??

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Cairo University
• Treatments: Povidone; Povidone-Iodine

Criteria

Inclusion Criteria:

• 1. Pregnant women who are 37 weeks gestation or more scheduled for elective caesarean section or those in labor with limited number of vaginal examination less than 5 times preoperatively.

2. Pregnant women who are 37 weeks gestation or more with rupture of membranes but duration less than 24 hours

3.Women consenting to be included in the study.

Exclusion criteria:

1. Abnormally invasive placenta and placenta previa.

2. Intra-partum fever.

3. Prolonged rupture of membranes more than 24 hours

4. History of exposure to radiation treatment for cancer.

5. History of Gynecological infections (PID).

6. History of abdominal infections eg: peritonitis.

7. Debilitating diseases like Diabetes mellitus, Thyroid disorders, Cushing disease, abdominal malignancy.

8. Obesity defined as pregnant BMI >30 kg/m2.

9. History of wound infection or burst abdomen.

10. History suggestive of massive bleeding during previous cesarean section.

11. allergy to iodine containing solutions

12. Pregnant women with severe anemia defined as Hb <7 g/dl.

13. Cases with intra-abdominal drain deployment are discarded.

14. Obstructed labor with numerous vaginal examinations.