Overview

Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

Status:
Active, not recruiting
Trial end date:
2022-11-15
Target enrollment:
Participant gender:
Summary
This pilot clinical trial studies vaccine therapy and temozolomide in treating patients with newly diagnosed glioblastoma. Vaccines made from a person's white blood cells mixed with tumor proteins may help the body build an effective immune response to kill tumor cells. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving vaccine therapy and temozolomide may be an effective treatment for glioblastoma.
Phase:
Early Phase 1
Details
Lead Sponsor:
Mayo Clinic
Collaborator:
National Cancer Institute (NCI)
Treatments:
Dacarbazine
Temozolomide
Vaccines