Vaccine Therapy With or Without Cyclophosphamide and Doxorubicin in Women With Stage IV Breast Cancer
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Vaccines made from a person's tumor cells may make the body build an immune
response to kill tumor cells. Drugs used in chemotherapy, such as cyclophosphamide and
doxorubicin, work in different ways to stop tumor cells from dividing so they stop growing or
die. Combining vaccine therapy with cyclophosphamide and doxorubicin may kill more tumor
cells.
PURPOSE: This phase I trial is studying the side effects and best dose of cyclophosphamide
and doxorubicin when given with vaccine therapy in treating women with stage IV breast
cancer.
Phase:
Phase 1
Details
Lead Sponsor:
Sidney Kimmel Comprehensive Cancer Center Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins