Vaccine Therapy, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status:
Completed
Trial end date:
2015-02-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Vaccines made from peptides may help the body build an effective immune response
to kill tumor cells. Drugs used in chemotherapy, such as temozolomide, work in different ways
to stop the growth of tumor cells, either by killing the cells or by stopping them from
dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving vaccine
therapy together with temozolomide and radiation therapy may kill more tumor cells.
PURPOSE: This phase I trial is studying the side effects of vaccine therapy when given
together with temozolomide and radiation therapy in treating patients with newly diagnosed
glioblastoma multiforme.