Vaccine Therapy Plus Sargramostim and Chemotherapy in Treating Women With Stage II or Stage III Breast Cancer
Status:
Completed
Trial end date:
2007-10-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Vaccines made from a gene-modified virus may make the body build an immune
response to kill tumor cells. Colony-stimulating factors such as sargramostim may increase
the number of immune cells found in bone marrow or peripheral blood. Drugs used in
chemotherapy use different ways to stop tumor cells from dividing so they stop growing or
die. Combining vaccine therapy with sargramostim and chemotherapy may kill more tumor cells.
PURPOSE: Randomized clinical trial to study the effectiveness of vaccine therapy plus
sargramostim and combination chemotherapy in treating women who have undergone surgery for
stage II or stage III breast cancer that has spread to the lymph nodes.