Vaccine Therapy, Chemotherapy, and GM-CSF in Treating Patients With Advanced Pancreatic Cancer
Status:
Completed
Trial end date:
2004-04-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Vaccines made from donated tumor cells treated with interferon alfa may make the
body build an immune response to and kill pancreatic tumor cells. Drugs used in chemotherapy
use different ways to stop tumor cells from dividing so they stop growing or die.
Colony-stimulating factors may help a person's immune system recover from the side effects of
chemotherapy. Combining these treatments may kill more tumor cells.
PURPOSE: Phase II trial to study the effectiveness of combining vaccine therapy using donated
tumor cells treated with interferon alfa and radiation therapy and cyclophosphamide plus
GM-CSF in treating patients with advanced pancreatic cancer.