Vaccine Biotherapy of Cancer: Autologous Tumor Cells and Dendritic Cells
Status:
Completed
Trial end date:
2007-09-01
Target enrollment:
Participant gender:
Summary
This protocol was conducted as a single institution trial at Hoag Cancer Center, Hoag
Hospital, Newport Beach, California. It was a single-arm phase II trial in which patients
with metastatic melanoma received subcutaneous (s.c.) injections of irradiated autologous
tumor cells that had been established as short-term cell lines, in conjunction with their own
dendritic cells (DC) and granulocyte macrophage colony-stimulating factor [GM-CSF]. Eligible
patients had regionally recurrent and/or distant metastatic cancer.