VNP40101M and Temozolomide in Treating Patients With Progressive or Relapsed Malignant Glioma
Status:
Terminated
Trial end date:
2009-10-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as temozolomide and VNP40101M, work in different
ways to stop the growth of tumor cells, either by killing the cells or by stopping them from
dividing. Temozolomide may also stop the growth of tumor cells by blocking blood flow to the
tumor.
PURPOSE: This phase I/II trial is studying the side effects and best dose of VNP40101M when
given together with temozolomide and to see how well it works in treating patients with
progressive or relapsed malignant glioma.