VIP: Vascular Imaging Project. Study on the Progression of Cardiovascular Disease in Renal Transplant Recipients
Status:
Completed
Trial end date:
2010-12-01
Target enrollment:
Participant gender:
Summary
This is a prospective randomized study to compare the influence of area under the curve
(AUC)-monitored dual treatment with steroids in combination with either a calcineurin
inhibitor (CNI) or mycophenolate mofetil (MMF) on the progression of subclinical
cardiovascular disease in renal transplant recipients.
Since CNI have a detrimental effect on cardiovascular risk factors, it is the researchers'
hypothesis that renal recipients after CNI withdrawal will have more reduction of markers of
cardiovascular disease.