Overview (VELA) Study of BLU-222 in Advanced Solid Tumors Status: Recruiting Trial end date: 2025-12-01 Target enrollment: Participant gender: Summary This is a Phase 1/2, open-label, first-in-human (FIH) study designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and anticancer activity of BLU-222, a selective inhibitor of CDK2. Phase: Phase 1/Phase 2 Details Lead Sponsor: Blueprint Medicines CorporationTreatments: CarboplatinFulvestrant