Uterine Electrical Activity Before and After Progesterone Treatment for Preterm Labor
Status:
Withdrawn
Trial end date:
2013-10-01
Target enrollment:
Participant gender:
Summary
This study will examine the effects of various formulations of progesterone on uterine
electromyographic (EMG) activity in pregnant patients in premature labor to determine if
progesterone will suppress uterine electrical activity and which formulation may be best for
inhibition of uterine activity. Patients will be monitored prior to treatment and following
treatment (every 2 to 4 hours) with one of three different formulations of progesterone for
up to two days. Patients will continue to be observed until they deliver. Comparisons will be
for uterine EMG activity from before treatment to that following treatments at 2, 4, 8, 12 24
and 48 hours and times of delivery after treatments (hours or days following treatments).
Comparisons between mean values for EMG activity between the various treatments at the
various times will also be made.