Using Ferumoxytol-Enhanced MRI to Measure Inflammation in Patients With Brain Tumors or Other Conditions of the CNS
Status:
Completed
Trial end date:
2017-01-12
Target enrollment:
Participant gender:
Summary
This pilot clinical trial study will assess the inflammatory response of brain tumors or
other central nervous system conditions in pediatric and adult patients using
ferumoxytol-enhanced MRI. Imaging features will be correlated with the number of inflammatory
cells (macrophages) at histopathology. Determining the extent of inflammation associated with
pathologies in the central nervous system may be helpful for diagnostic and prognostic
purposes as well as monitoring treatment response of current and future immunotherapies.