Isolated urticaria in the emergency department is widely treated by physicians with histamine
blocking agents such as diphenhydramine, cetirizine, and cimetidine. Doxepin is a tricyclic
antidepressant that has been shown to have much higher concentrations of histamine blocking
activity and therefore may be useful in treating urticaria. The purpose of this study is to
compare the effectiveness of using doxepin verses a traditional medication, diphenhydramine
(Benadryl), in the treatment of isolated urticaria in the emergency department.
Phase:
Phase 3
Details
Lead Sponsor:
State University of New York - Upstate Medical University