Overview

Using Donor Stem Cells and Alemtuzumab to Prevent Organ Rejection in Kidney Transplant Patients

Status:
Completed
Trial end date:
2009-11-01
Target enrollment:
Participant gender:
Summary
Alemtuzumab is a man-made antibody used to treat certain blood disorders. This study will evaluate treatment of kidney transplant recipients with alemtuzumab and other immune system suppressing medications with or without infusions of bone marrow stem cells from the kidney donor. The purpose of this study is to find out which strategy is more effective in preventing organ rejection and maintaining patient health.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
University of Miami
Collaborator:
Immune Tolerance Network (ITN)
Treatments:
Alemtuzumab
Mycophenolate mofetil
Mycophenolic Acid
Sirolimus
Tacrolimus