Use of Ulipristal Acetate in Induction of Second Trimester Missed Abortion
Status:
Completed
Trial end date:
2020-01-01
Target enrollment:
Participant gender:
Summary
The aim of this work is to assess the effectiveness and safety of Ulipristal Acetate in the
management of 2nd trimester missed abortion along with misoprostol in pregnant women with
previous caesarean section versus the use of misoprostol only with placebo as regards the
time needed for abortion,Hypothesis: In pregnant women with 2nd trimester missed abortion
with previous caesarean section , Ulipristal Acetate may decrease the time interval to
achieve abortion when combined with Misoprostol in comparison to misoprostol alone.the
included women divided to 2 groups Group A: will receive Ulipristal acetate 30mg, starting
misoprostol 12 hours later 100µg every 6 hours buccal according to FIGO guidelines 2017.Group
B: will receive placebo then 12 hours later start misoprostol 100µg every 6 hours buccal
according to FIGO guidelines 2017. then we assess Induction-to-abortion interval time.