Use of Sildenafil (Viagra) in Diabetic Men With Erectile Dysfunction: the Impact on Blood Vessels
Status:
Completed
Trial end date:
2007-12-01
Target enrollment:
Participant gender:
Summary
- To evaluate the impact of nightly sildenafil vs placebo use on diabetic men with and
without proven endothelial dysfunction and coexisting erectile concerns.
- To determine if chronic sildenafil use compared to placebo positively impacts
endothelial function among a cohort of diabetic mend with erectile dysfunction
- To assess the salvage rate of sildenafil - failures who demonstrate improved response
rates over time with chronic use
- To assess if microalbuminuria predicts flow-mediated dilation (FMD) response
- To measure and identify if other patient specific characteristics predict for sildenafil
erectile response and flow-mediated dilatation (FMD) response over time (patient
specifics; blood pressure, HBA1c, weight, BMI, age IIEF score at baseline)