Overview

Use of Prophylactic Steroids in the Prevention of Post-thyroidectomy Hypocalcaemia and Voice Dysfunction

Status:
Completed
Trial end date:
2020-07-01
Target enrollment:
0
Participant gender:
All
Summary
Total thyroidectomy for benign surgical pathologies is associated with risks related to temporary hypocalcaemia and vocal quality dysfunction. Dexamethasone, as an anti-inflammatory steroid, has been proposed to have a physiological effect on hypocalcaemia and voice quality. Investigators conducted a double-blinded controlled trial to assess the effect of preoperative dexamethasone on the vocal dysfunction and hypocalcaemia following thyroidectomy
Phase:
N/A
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Holy Family Hospital, Pakistan
Treatments:
Dexamethasone
Criteria
Inclusion Criteria:

- Benign thyroid condition.

- Patients without any preoperative corrected hypocalcaemia and voice or vocal quality
dysfunction.

Exclusion Criteria:

- Previous thyroid or neck surgery

- Known vocal cord dysfunction on laryngoscopy

- Hearing or voice problems

- History of gastroesophageal reflux and stomach ulcer disease

- Contraindications of steroids